Professor Surjit Singh, India
MAJOR ACADEMIC CONTRIBUTIONS AND SIGNIFICANCE:
The various aspects of clinical toxicology including pattern of acute poisoning and change in it in admitted patients between 1970-2004 was studied in institute and reported both in adults and children. The role of upper G. I. endoscopy and feeding jejunostomy in corrosive acid poisoning was investigated and established in 1984. The first large series in literature on aluminium phosphide ingestion was described in 1985. The first case of Methyl Isocynate poisoning was published in BMJ in 1983 only case available before Bhopal tragedy. The role of atropine alone and with high dose continuous 2-PAM in severe organophosphorous was investigated and published by 2001. Clinico-pathologic findings in 190 cases of ALP have been described. Role of platelet cytochrome-C activation inhibition in ALP poisoning has been published. Numerous other poisonings and their clinical features and autopsy findings have been have been published including human poisoning of maduramycin, the first ever recorded cases in humans in literature. The role of neostigmine in krait bite was investigated and its limitations described.
The other area of interest are esterases especially paraoxonase activity. The paraoxonase1(PON1) activity and its role in CAD in North West Indian Punjabi’s has been published (first to be described in any ethnic group in India). Its gene polymorphism both coding and promoter were investigated in CAD patients with and without Type II diabetes and results have been published. PON3 activity and its gene polymorphism both coding and promoter were investigated in CAD patients and 3 papers has been submitted for publication.
.In 2007, I was made head of clinical immunology and rheumatology division and started DM in this. Retired in July 2016 and since then at home.
Prof Geoff Isbister
Prof. Isbister is a clinician researcher in clinical toxicology at University of Newcastle, Australia. His research has focused on understanding poisoning and envenoming in patients and undertaking studies to determine the effectiveness of antidotes and antivenoms in treatment of these conditions. He heads the Clinical Toxicology Research Group at the University. He has published over 250 original research publications and holds an NHMRC Senior Research Fellowship as well as being Chief Investigator on an NHMRC Program Grant and an NHMRC Centre for Research Excellence on Translational Venom and Antivenom Research. The benefits of the research include improving our understanding of the pathophysiology of both envenomation and poisoning. Much of his research challenges long held views about the treatment of poisoned and envenomed patients, including whether antivenom works. He has made clinicians re-look at what evidence there is for various treatments and why we use these treatments.
Prof. Tharaka Dassanayake
Prof. Dassanayake is a Professor in Neurophysiology at the Faculty of Medicine University of Peradeniya and an Honorary Consultant Neurophysiologist at the Teaching Hospital Peradeniya. He obtained his MBBS and MPhil from University of Peradeniya and his PhD from The University of Newcastle, Australia.
His primary research interests are clinical neurophysiology and cognitive neurosciences. His research at the South Asian Clinical Toxicology Research Collaboration focuses on neurocognitive effects of organophosphorus pesticides and sedative medications.